Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Flna  filamin, alpha   (Synonyms: ABP-280, actin-binding protein 280, Dilp2, F730004A14Rik, filamin-1, Fln1, GENA 379)
Results	Reference
1*	J:132026 Farrington-Rock C, Kirilova V, Dillard-Telm L, Borowsky AD, Chalk S, Rock MJ, Cohn DH, Krakow D, Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome. Hum Mol Genet. 2008 Mar 1;17(5):631-41
1*	J:241779 Hu J, Lu J, Goyal A, Wong T, Lian G, Zhang J, Hecht JL, Feng Y, Sheen VL, Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading. Hum Mol Genet. 2017 Apr 01;26(7):1294-1304
1	J:246267 Juo LY, Liao WC, Shih YL, Yang BY, Liu AB, Yan YT, HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles. J Cell Sci. 2016 Apr 15;129(8):1661-70
1	J:237533 Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, Sheen V, Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016 Dec 01;143(23):4509-4520
1	J:244557 Liao WC, Juo LY, Shih YL, Chen YH, Yan YT, HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity. PLoS Genet. 2017 Aug;13(8):e1006984
1*	J:234716 Segura I, Lange C, Knevels E, Moskalyuk A, Pulizzi R, Eelen G, Chaze T, Tudor C, Boulegue C, Holt M, Daelemans D, Matondo M, Ghesquiere B, Giugliano M, Ruiz de Almodovar C, Dewerchin M, Carmeliet P, The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A. Cell Rep. 2016 Mar 22;14(11):2653-67
1	J:79977 Sheen VL, Feng Y, Graham D, Takafuta T, Shapiro SS, Walsh CA, Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact. Hum Mol Genet. 2002 Nov 1;11(23):2845-54
1*	J:269148 Urra H, Henriquez DR, Canovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic A, Gonzalez-Billault C, Hetz C, IRE1alpha governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A. Nat Cell Biol. 2018 Aug;20(8):942-953
1*	J:260692 Yagi H, Nagano T, Xie MJ, Ikeda H, Kuroda K, Komada M, Iguchi T, Tariqur RM, Morikubo S, Noguchi K, Murase K, Okabe M, Sato M, Filamin A-interacting protein (FILIP) is a region-specific modulator of myosin 2b and controls spine morphology and NMDA receptor accumulation. Sci Rep. 2014 Sep 15;4:6353
1	J:187673 Zhang J, Neal J, Lian G, Shi B, Ferland RJ, Sheen V, Brefeldin A-inhibited Guanine Exchange Factor 2 Regulates Filamin A Phosphorylation and Neuronal Migration. J Neurosci. 2012 Sep 5;32(36):12619-29
1	J:236302 Zhang X, Chen MH, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA, Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell. 2016 Aug 25;166(5):1147-1162.e15